Report on microbial aggregation (clustering) by 2QR-complex polysaccharides

Pathogenic microorganisms have developed tools to breach the natural host defense system to colonize and invade our tissues. The majority of microbial problems are initiated by adhesion of harmful microorganisms to human epithelial surfaces (skin and mucosa) (1, 2). To effectively bind to host tissue surfaces, many microorganisms possess multiple adhesin proteins on their outer surface. These adhesins bind to polysaccharide groups that are present on receptor molecules at the surface of our epithelial cells (3).